The lancet oncology
The most recent articles from:
Lancet Oncol.
-
The lancet oncology · Dec 2020
Randomized Controlled Trial Multicenter StudyInternal mammary and medial supraclavicular lymph node chain irradiation in stage I-III breast cancer (EORTC 22922/10925): 15-year results of a randomised, phase 3 trial.
10-year results from several studies showed improved disease-free survival and distant metastasis-free survival, reduced breast cancer-related mortality, and variable effects on overall survival with the addition of partial or comprehensive regional lymph node irradiation after surgery in patients with breast cancer. We present the scheduled 15-year analysis of the European Organisation for Research and Treatment of Cancer (EORTC) 22922/10925 trial, which aims to investigate the impact on overall survival of elective internal mammary and medial supraclavicular (IM-MS) irradiation. ⋯ US National Cancer Institute, Ligue Nationale contre le Cancer, and KWF Kankerbestrijding.