The lancet oncology
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Lancet Oncol.
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The lancet oncology · Jul 2016
Randomized Controlled Trial Multicenter StudySPAG5 as a prognostic biomarker and chemotherapy sensitivity predictor in breast cancer: a retrospective, integrated genomic, transcriptomic, and protein analysis.
Proliferation markers and profiles have been recommended for guiding the choice of systemic treatments for breast cancer. However, the best molecular marker or test to use has not yet been identified. We did this study to identify factors that drive proliferation and its associated features in breast cancer and assess their association with clinical outcomes and response to chemotherapy. ⋯ Nottingham Hospitals Charity and the John and Lucille van Geest Foundation.