Modern rheumatology
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Modern rheumatology · Jan 2016
Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) were useful markers in assessment of inflammatory response and disease activity in SLE patients.
Although there have been extensive investigations on neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and mean platelet volume (MPV) in many diseases, their roles in systemic lupus erythematosus (SLE) remain unclear. The purpose of the present study was to evaluate NLR, PLR, and MPV levels in adult SLE patients and explore their clinical significance. ⋯ NLR and PLR could reflect inflammatory response and disease activity in SLE patients.
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Modern rheumatology · Jan 2016
Review Meta AnalysisRisk of ischemic stroke in patients with systemic sclerosis: A systematic review and meta-analysis.
Several chronic inflammatory disorders, such as rheumatoid arthritis and idiopathic inflammatory myositis, have been shown to increase risk of ischemic stroke but the data on systemic sclerosis (SSc) remains unclear. ⋯ Our study demonstrated a statistically significant increased ischemic stroke risk among patients with SSc.
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Modern rheumatology · Jan 2016
Epidemiologic analysis of the clinical features of Japanese patients with polymyositis and dermatomyositis.
This study aimed to investigate the clinical characteristics of polymyositis/dermatomyositis (PM/DM) in Japan by analyzing data from the nationwide registration system. ⋯ The results characterize significant aspects of Japanese PM/DM patients. However, a further prospective survey is required to clarify the true epidemiology and natural history of PM/DM.
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Modern rheumatology · Nov 2015
Systemic sclerosis and risk of venous thromboembolism: A systematic review and meta-analysis.
Several chronic inflammatory disorders, such as rheumatoid arthritis, inflammatory myositis, and systemic vasculitides, have been linked to an increased risk of venous thromboembolism (VTE). However, the data on systemic sclerosis (SSc) remains unclear. ⋯ Our study demonstrated a statistically significant increased VTE risk among patients with SSc.