Laboratory animal science
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Rhinosporidiosis is a fungal infection caused by Rhinosporidium seeberi, a microorganism of complicated, undetermined life cycle. Many species of animals are susceptible to rhinosporidiosis, including human beings. ⋯ A one-year-old male Collie dog from Northeast Arkansas was found to have rhinosporidiosis presenting as an intranasal polypoid mass. We believe this is the first documented report of rhinosporidiosis from the State of Arkansas.
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Laboratory animal science · Aug 1985
Non-invasive blood pressure measurement in Yucatan miniature swine using tail cuff sphygmomanometry.
A relatively new non-invasive method using a photo-electric flow sensor in non-heated animals, was evaluated for its accuracy in measuring systolic blood pressure (SBP), diastolic blood pressure (DBP) and mean arterial pressure (MAP) in 40-90 Kg normotensive and hypertensive Yucatan miniature swine. Directly measured SBP, DBP and electronically averaged MAP were recorded from chronic arterial catheters simultaneously with indirect pressures, cuff pressure and tail blood flow under various conditions. In all of the tests tail cuff SBP estimation averaged within 5% of directly measured SBP. ⋯ The measured tail cuff MAP generally underestimated the direct MAP by approximately 5%. The correlation of directly measured MAP and tail cuff methods was significant (r = .72, P less than 0.01). These results indicated that this system may be used to accurately assess blood pressure in miniature swine.
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Laboratory animal science · Oct 1978
ReviewThe influence of chemical restraining agents on cardiovascular function: a review.
A review of selected experimental reports indicated that chemical restraining agents commonly used in experimental animals affected basal cardiovascular function and could influence the response of the cardiovascular system to physiologic-pharmacologic stimuli. Drugs that were considered included pentobarbital, halothane, alpha-chloralose, droperidol, fentanyl, and ketamine. In relation to effects on hemodynamics, anesthetic restraint produced by one drug was not necessarily equivalent to that produced by another.
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A simple artificial respiration mask for rats was constructed from the drip chamber of an intravenous solution administration set. The mask was held in place by means of straps and a hole through which the maximillary incisors protruded. This mask permitted artificial ventilation during drug-induced respiratory paralysis, was easily and inexpensively constructed, and may be used with a variety of positive pressure respirators.
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Laboratory animal science · Oct 1975
Sheep: a model for testing spinal and epidural anesthetic agents.
The sheep was utilized as a model to study local anesthetic agents used for subarachnoid and epidural anesthesia in human beings. Employing injection and evaluation technics similar to those used in human anesthesiology, the onset of anesthesia, development of maximum sensory anesthesia, regression of sensory anesthesia, and complete return of sensation and motor function were measured. Subarachnoid injection with 0.25% tetracaine and epidural injection with 0.25% bupivacaine produced regional anesthesia similar to that observed in humans.