Emergency medicine journal : EMJ
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There is substantial interest in blood biomarkers as fast and objective diagnostic tools for traumatic brain injury (TBI) in the acute setting. ⋯ S100B, H-FABP, NF-L and IL-10 levels in patients with mTBI were significantly lower than in patients with moTBI and sTBI but alone or in combination, were unable to distinguish patients with mTBI from orthopaedic controls. This suggests these biomarkers cannot be used alone to diagnose mTBI in trauma patients in the acute setting.
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Clinical introductionA healthy 17-year-old girl presents with a wound on her left medial thigh (figure 1). Two days earlier while applying acrylic nail tips, she spilled nail glue on her jeans in the area of concern. Despite noticing an immediate irritable sensation, she did not perform any first aid nor did she remove her clothing to check the underlying skin.emermed;39/3/185/F1F1F1Figure 1Wound left medial thigh. ⋯ Partial thickness thermal burn. Allergic reaction to nail glue. For answer see page 02.
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A short-cut review of the available medical literature was carried out to establish whether elbow immobilisation is required after closed reduction of a distal radial fracture. After abstract review, six papers were found to answer this clinical question using the detailed search strategy. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. It is concluded that elbow immobilisation is not required.