Heart, lung & circulation
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Heart, lung & circulation · Jun 2015
Comparative StudyPlatelet distribution width and mean platelet volume in idiopathic pulmonary arterial hypertension.
Previous studies have demonstrated that platelet activation occurs in patients with pulmonary arterial hypertension (PAH). Mean platelet volume (MPV) and platelet distribution width (PDW) are two markers of platelet activation, and have recently been recognised as risk predictors of cardiovascular diseases. This study aimed to investigate whether MPV and PDW would be useful to reflect disease severity and predict prognosis in idiopathic PAH (IPAH). ⋯ Our results suggest that MPV and PDW were elevated in patients with IPAH. They could partly reflect disease severity, but did not predict prognosis.
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Heart, lung & circulation · Jun 2015
Observational StudyImpact of anaemia on mortality and its causes in elderly patients with acute coronary syndromes.
Prognostic impact of anaemia in the elderly with acute coronary syndromes has not been specifically analysed, and little information exists about causes of mortality in this setting. ⋯ The impact of anaemia on cause specific of mortality seem to be different according to age subgroup. The association between anaemia and mortality was not observed in elderly patients from our series.