Clinical medicine (London, England)
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An outbreak of acute hepatitis C among HIV-positive men who have sex with men (MSM) in the last decade has been shown to be sexually transmitted. Initially recreational drug use, in particular drug injection, was not prevalent among those becoming infected with hepatitis C. ⋯ It is hoped that the widespread -introduction of direct-acting antivirals and upscaling of numbers treated may have a positive impact on this epidemic. However their introduction may negatively impact on the perceived risk of acquiring hepatitis C and in conjunction with the introduction of HIV transmission prevention strategies may result in increased transmissions and spread to the HIV-negative MSM population.
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Ambulatory care sensitive conditions (ACSCs) are a group of conditions judged to be suitable for healthcare efficiency initiatives to reduce the rate of hospital admissions. All emergency medical admissions to an Irish hospital between 2002 and 2013 were assessed for ACSCs. They were categorised by quintile of deprivation index and evaluated against hospital admission rate. ⋯ ACSCs represented 66.4% of admissions. The rate of ACSC admissions increased with deprivation index, Q1 10.4 (95% confidence interval (CI) 10.2-10.5), Q2 17.3 (95% CI 17.2-17.5), Q3 34.0 (95% CI 33.7-34.2), Q4 30.2 (95% CI 30.0-30.4) and Q5 44.5 (95% CI 43.8- 45.1) (p<0.001), corresponding incidence rate ratios compared with Q1 were: Q2 1.67 (95% CI 1.64-1.70), Q3 3.28 (95% CI 3.22-3.33), Q4 2.92 (95% CI 2.87-2.97) and Q5 4.29 (95% CI 4.20-4.39) (p<0.001). ACSCs are common in acute medical admissions and are strongly influenced by the underlying social demographics of the population.
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Written knowledge assessments for physicians in training typically involve multiple-choice questions that use a clinical scenario in a single-best-answer format. The Royal College of Physicians Part 1 MRCP(UK) examination includes basic sciences themes that are challenging to assess through a clinical scenario. ⋯ Reading unnecessary material frustrates candidates and threatens the reputation of the assessment. In this paper we discuss why a clinical scenario is important for basic science questions and offer advice on setting realistic and plausible clinical scenarios for such questions.
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Syphilis is caused by the spirochete bacteriumTreponema pallidumand can be transmitted both sexually and from mother to child. T pallidumcan infect any organ and produces a clinical disease with a relapsing and remitting course. It is not hard to see, therefore, why it is often described as the great mimic. In this review, we provide an update of modern syphilis epidemiology, clinical presentations, and testing and treatment strategies.