Internal medicine journal
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Internal medicine journal · May 2012
Leukaemic transformation of Philadelphia chromosome-negative myeloproliferative neoplasms: are Asian patients different?
Leukaemic transformation (LT) is rare in the natural history of Philadelphia(Ph) chromosome-negative myeloproliferative disorders (MPD), and has a dismal prognosis. Little literature is available on Asian patients. ⋯ LT of Ph chromosome-negative MPD is rare and uniformly fatal. Despite chemotherapy, survival was poor, and patients succumbed to refractory disease and infections. Asian patients did not have a more favourable outcome. It remains to be investigated whether upfront stem cell transplant may be a treatment option.
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Internal medicine journal · May 2012
Case ReportsUtility of atrial temporary pacing as an acute treatment for bradyarrhythmias and tachyarrhythmias in the intensive care setting with preservation of atrioventricular synchrony.
Temporary pacing is often used as an acute treatment of bradyarrhythmias and suppression of tachyarrhythmias. In patients with cardiogenic shock, loss of atrioventricular synchrony may worsen cardiovascular haemodynamics. We present a series where temporary right atrial pacing was used as an acute treatment for both bradyarrhythmias and tachyarrhythmias.
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Internal medicine journal · May 2012
Staphylococcus aureus bacteraemia at Alice Springs Hospital, Central Australia, 2003-2006.
Infectious diseases remain the leading cause of death at Alice Springs Hospital (ASH) and Staphylococcus aureus bacteraemia (SAB) is the second most common bloodstream infection. Non-multidrug-resistant, methicillin-resistant S. aureus (nmMRSA) is endemic to the region. ⋯ Indigenous Australians have the highest reported incidence rate of SAB worldwide. This reflects the socioeconomic disadvantage experienced by indigenous Australians whose living conditions predispose to pathogen transmission and limits opportunities to maintain adequate skin hygiene.