Internal medicine journal
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Internal medicine journal · Jun 2022
Clinicopathological characteristics and clinical morbidity in high-risk head and neck cutaneous squamous cell carcinoma patients in Western Australia.
There is no registry data on morbidity and mortality of high-risk cutaneous squamous cell carcinoma (cSCC) in Australia. ⋯ High-risk cSCC patients have significant health needs represented by high-baseline comorbidities, multiplicity of cSCC events and the number of healthcare-associated interventions. There is an unmet need for robust cancer data collection.
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Internal medicine journal · Jun 2022
Observational StudyPatterns of azithromycin use in obstructive airway diseases: a real-world observational study.
Low-dose long-term azithromycin is recommended in clinical practice guidelines for obstructive airway diseases (OAD); however, an optimal therapeutic regimen is not yet established. ⋯ Physicians are currently using low-dose azithromycin for a long duration of more than 1 year for the management of OAD. The typical case definition is an older non-smoking adult with persistent asthma, often in combination with another OAD and presenting with bothersome cough or sputum. Azithromycin was well tolerated and led to reduced healthcare utilisation. Further research is required to establish an optimal dosage regimen of azithromycin in OAD.
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Internal medicine journal · Jun 2022
Case ReportsUnusual presentations of central nervous system myeloid sarcoma.
Myeloid sarcoma (MS), also termed 'chloroma' or 'granulocytic sarcoma', is a tumour mass consisting of myeloid blasts occurring at an anatomical site other than the bone marrow. MS occurs in up to 8% of patients with acute myeloid leukaemia. ⋯ We present a case series of patients that presented to a tertiary hospital with MS affecting the central nervous system over a 4-month period. These three cases demonstrate the vast spectrum of clinical presentations of MS and, furthermore, show rare examples of intramedullary spinal cord involvement and disseminated intraparenchymal brain disease.
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Internal medicine journal · Jun 2022
Too much sugar does not just make us fat; it can also make us sick.
The post-COVID-19 care era is likely to see a burgeoning of metabolic dysfunction and chronic kidney disease. Attention to self-care, including nutrition, will underpin the management of those affected. The damaging effects of sugar-sweetened beverages are well documented and profound and counter many accepted medical treatments. Government leadership is urgently required with explicit and strong messaging to avoid sugar-sweetened beverages.
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Internal medicine journal · Jun 2022
ReviewArtificial Intelligence in Cardiology: Fundamentals and Applications.
Artificial intelligence (AI) is an overarching term that encompasses a set of computational approaches that are trained through generalised learning to autonomously execute specific tasks. AI is a rapidly expanding field in medicine. In particular cardiology, with its high reliance on numerical patient data in decision making, has great potential to benefit from AI. ⋯ Healthcare systems will undoubtedly become more automated and shift to more AI-driven methods to improve efficiency and reduce cost. Patients in the end will benefit from these changes with improved diagnostic accuracy, better tailored treatments resulting in a greater quality and quantity of life. In this article, we will describe some of the fundamental principles underlying AI that physicians should have an understanding of, along with current clinical applications.