Internal medicine journal
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Internal medicine journal · Jun 2024
Observational StudyEffects of nonprescription therapies on vestibular migraine: a questionnaire-based observational study.
Vestibular migraine (VM) is a common cause of recurrent vertigo. Migraine headache preventative therapies are currently prescribed to control vertigo symptoms in VM. Clinical trials of nutraceuticals for migraine headache prevention have shown positive outcomes, but, to date, there have been no studies to assess their effectiveness in the management of VM. ⋯ The results provide preliminary evidence that VM symptom frequency and severity can be reduced by using nonprescription therapies.
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Internal medicine journal · Jun 2024
Comparative StudyA comparison between erythrocytapheresis and venesection for the treatment of JAK2-mutated polycythaemia.
JAK2-mutated polycythaemia vera (PV) is associated with reduced survival because of thrombotic events and haematological disease transformation. Therapeutic venesection has traditionally been used to lower haematocrit, but the technique of erythrocytapheresis has emerged over the last decade. ⋯ Erythrocytapheresis is more efficacious than venesection for the treatment of PV and is accompanied by rapid reductions in haematocrit and reduced thrombotic complications.
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Internal medicine journal · Jun 2024
Fabry-specific treatment in Australia: time to align eligibility criteria with international best practices.
Disease-specific therapy aims to improve symptoms, stabilise current disease and delay progression in patients with Fabry disease. In Australia, treatment access is subject to eligibility criteria initially established in 2004. Patients and their clinicians question why these criteria have remained unchanged despite significant progress in disease understanding. ⋯ Australian access criteria are misaligned with current clinical evidence. The clinical statements and proposed classification and initiation criteria should prompt discussions to support more equitable access to treatment and better align Australian practice with contemporary evidence and international guidelines.
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Internal medicine journal · Jun 2024
Medications and cognitive risk in Aboriginal primary care: a cross-sectional study.
Aboriginal and Torres Strait Islander people are ageing with high rates of comorbidity, yet little is known about suboptimal prescribing in this population. ⋯ Associations between potentially suboptimal prescribing and depression or cognitive concerns highlight the importance of considering medication review and deprescribing for these patients.