Internal medicine journal
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Internal medicine journal · Nov 2018
Comparative StudyEvaluation of chronic kidney disease in cancer patients: is there a preferred estimation formula?
The evaluation of chronic kidney disease (CKD) in cancer patients seems to rely mostly on the Cockcroft-Gault (CG) formula or the creatinine levels to adjust treatment dosages which is a practice refuted by internists. ⋯ The newly proposed JW eGFR estimation was more in agreement with CG equation than the other equations.
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Internal medicine journal · Nov 2018
Diagnostic yield of pleural fluid cytology in malignant effusions: an Australian tertiary centre experience.
Timely diagnosis of malignant pleural effusions is critical to guide prognosis and management decisions. Cytological analysis of pleural fluid has been the first-line diagnostic test for many decades, with highly variable reported sensitivities of 40-90%. Its diagnostic accuracy in modern practice in Australia needs to be understood. ⋯ Tumour type is an important determinant of pleural fluid cytology diagnostic yield. Cytology has good sensitivity and specificity for the diagnosis of adenocarcinoma, but if another tumour type is suspected, particularly mesothelioma, clinicians should be aware of the limitations.
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Internal medicine journal · Oct 2018
Temporal changes in glycaemic thresholds for treatment intensification in type 2 diabetes in an urban Australian setting: the Fremantle Diabetes Study.
Pharmacotherapy and supportive care for diabetes in Australia are improving, with potential beneficial effects on therapeutic procrastination. ⋯ HbA1c thresholds triggering treatment intensification fell between FDS phases, suggesting a more proactive approach to management of glycaemia over time.
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Internal medicine journal · Sep 2018
Multicenter StudyClinical risk factors for acute ischaemic and haemorrhagic stroke in patients with infective endocarditis.
Stroke as a complication of infective endocarditis portends a poor prognosis, yet risk factors for stroke subtypes have not been well defined. ⋯ Among patients with IE, there exist characteristics that relate differentially to ischaemic and haemorrhagic stroke risk.