Internal medicine journal
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Internal medicine journal · Apr 2008
Letter Case ReportsAtypical case of Herpes simplex encephalitis.
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Internal medicine journal · Mar 2008
Recombinant activated factor VII in critical bleeding: experience from the Australian and New Zealand Haemostasis Register.
There has been increasing off-label use of recombinant activated factor VII (rFVIIa/NovoSeven; Novo Nordisk, Bagsvaerd, Denmark) for patients with critical bleeding. Given the lack of high-level evidence, the clinical indications, observed response and adverse events are important to capture. ⋯ The Haemostasis Registry cannot replace well-designed prospective randomized controlled trials, but in their absence this registry provides a basis for understanding current clinical experience of rFVIIa. Registries continue to be vital in monitoring off-label uses of medications.
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Internal medicine journal · Mar 2008
Empiric antibiotic prescribing for patients with community-acquired pneumonia: where can we improve?
Community acquired pneumonia is one of the most common infections for which antibiotics are prescribed in Australia. ⋯ Efforts to improve prescribing practices could be focused towards identifying patients with severe illness early and improving recognition of documented allergies.