The spine journal : official journal of the North American Spine Society
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Destabilization of the lumbar spine results from sacrifice of the anterior longitudinal ligament and disc when removed for graft or cage placement. In a similar fashion, transection of the interspinous ligament during surgical approaches to the posterior spine may result in segmental instability. Such instability can cause abnormal motion or implant migration resulting in a higher incidence of pseudarthrosis. Small intestinal submucosa (SIS) is a naturally occurring extracellular collagen-based matrix, which is derived from porcine small intestine. SIS contains cytokines and growth factors and has been shown to act as a resorbable scaffold in vivo that promotes host soft tissue regeneration with little scar tissue formation. SIS can be manufactured in laminated sheets of various sizes and thicknesses for different indications. Successful applications of SIS in animals have included dural substitution, rotator cuff repair, vessel repair, abdominal and bladder wall repair, and others. However, SIS has not been investigated to determine its ability to facilitate regeneration of spinal ligaments. ⋯ In this model, the SIS patch was sufficient to prevent acute ventral migration of interbody spacers from the disc space. The extent of long-term healing and new tissue formation in the SIS group indicates that it may be efficacious as a reparative intervention for transected ligaments in the spine. Most SIS specimens showed formation of organized collagenous tissue, indicating a long-term potential for ligament formation. However, in this model, 12 weeks of postoperative healing is insufficient to assess the full potential of SIS as a spinal ligament repair. Further research that follows the healing process to a longer time point postoperatively may be necessary to fully understand the potential of SIS as a resorbable scaffold for tissue replacement.
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Since the introduction of threaded devices in the mid-1990s, anterior lumbar interbody fusion (ALIF) has become a staple in the armamentarium of the spine surgeon. The procedure, however, is heavily dependent on the ability of the approach surgeon to provide exposure quickly and safely in view of a reported incidence of vascular injury as high as 15% and 2.3% incidence of retrograde ejaculation. ⋯ This experience suggests that a well-planned small incision that preserves the musculature can be performed quickly and safely to allow the spine surgeon adequate access to the anterior lumbar spine. The learning curve, however, can be high even for experienced surgeons.
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Techniques in current use for expansive laminoplasty operations (ELAP) on the cervical spine damage the extensor mechanisms, resulting in restriction of neck motion, loss of lordosis and persistent axial pains. ⋯ Skip laminectomy for cervical spinal canal decompression is less invasive than conventional laminectomy and ELAP. It is effective in preventing postoperative problems, such as persistent axial symptoms, restriction of neck motion and loss of cervical lordosis.