Pain practice : the official journal of World Institute of Pain
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Randomized Controlled Trial Multicenter Study
A double-blind, randomized, placebo-controlled study of the efficacy and safety of duloxetine for the treatment of chronic pain due to osteoarthritis of the knee.
To evaluate the efficacy and safety of duloxetine in the treatment of chronic pain due to osteoarthritis of the knee. ⋯ Treatment with duloxetine 60 mg to 120 mg QD was associated with significant pain reduction and improved function in patients with pain due to osteoarthritis of the knee.