Articles: trauma.
-
Eur J Trauma Emerg S · Apr 2011
Muscle regeneration is undisturbed by repeated polytraumatic injury.
Clinical observations suggest that repeated injury within a week after a traumatic event impairs the regeneration of tissues. Our aim was to investigate the effect of repeated trauma on the proliferation of satellite cells in skeletal muscle tissue. ⋯ The second hit phenomenon is probably due to systemic factors rather than to a diminished regenerating potential of injured soft tissues.
-
Clin. Orthop. Relat. Res. · Mar 2011
ReviewSpinal cord injury: a systematic review of current treatment options.
Spinal cord injury (SCI) is a devastating event often resulting in permanent neurologic deficit. Research has revealed an understanding of mechanisms that occur after the primary injury and contribute to functional loss. By targeting these secondary mechanisms of injury, clinicians may be able to offer improved recovery after SCI. ⋯ As our understanding of the fundamental mechanisms of SCI improves, we must keep abreast of these discoveries to translate them into therapies that will hopefully benefit patients. We summarize this process of bench to bedside with regard to SCI.