Articles: opioid-analgesics.
-
Retrospective study. ⋯ 4.
-
European urology focus · Jul 2020
Persistent Opioid Use Among Patients with Urolithiasis: A Population based Study.
Urolithiasis can result in acute, short-lived pain for which opioids are often prescribed. The risk of persistent opioid use following an initial presentation for urolithiasis is unknown. ⋯ In this study we found that 9% of patients prescribed opioids at presentation for kidney stones filled an additional prescription 3-6 mo later. Risk factors for this continued use included a higher dose of opioids prescribed in the initial period and the type of kidney stone surgery.
-
Hitherto only studies with selected populations have found an increased all-cause mortality of some selected opioids compared to selected non-opioids for chronic non-cancer pain (CNCP). We have examined the all-cause mortality for CNCP associated with all established opioids compared to non-opioid analgesic therapy (anticonvulsants, antidepressants, dipyrone, non-steroidal agents). ⋯ LTOT for CNCP compared to non-opioid analgesics was associated with an increased risk for all-cause mortality. When considering treatment options for patients with CNCP, the relevant risk of increased all-cause mortality with opioids should be discussed.
-
Letter Case Reports
Switching From High-Dose, Long-Term Opioids to Buprenorphine: A Case Series.
-
We hypothesised that Calabadion 1, an acyclic cucurbit[n]uril molecular container, reverses fentanyl-induced respiratory depression and dysfunction of the CNS. ⋯ Calabadion 1 selectively and dose dependently reversed the respiratory system and CNS side-effects of fentanyl.