Articles: surgery.
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Pathological features such as tumour type, tumour size and lymph node invasion have an important bearing on the prognosis of the patient with breast cancer. It is suggested that such prognostic factors should be considered in the selection of women for post-mastectomy breast reconstruction. The implications of pathological and other factors are reviewed and a summary of favourable prognostic factors is presented.
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Randomized Controlled Trial Clinical Trial Controlled Clinical Trial
Analgesic combinations with orphenadrine in oral post-surgical pain.
Two hundred male and female patients underwent a variety of oral surgical procedures and were treated afterwards in four test groups. They took a combination of orphenadrine (25 mg) and acetaminophen (325 mg), either drug alone, or placebo. A double-blind study design was used. ⋯ Each active drug, in turn, was also significantly better throughout than placebo for pain relief. Sub-groups in each treatment regimen required additional pain relief prior to six hours, with significantly more placebo than orphenadrine-acetaminophen patients needing remedication. Side-effect incidence was very low and randomly distributed among the four groups.