Articles: traumatic-brain-injuries.
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J Magn Reson Imaging · Jan 2014
Impact of reduced k-space acquisition on pathologic detectability for volumetric MR spectroscopic imaging.
To assess the impact of accelerated acquisitions on the spectral quality of volumetric magnetic resonance spectroscopic imaging (MRSI) and to evaluate their ability in detecting metabolic changes with mild injury. ⋯ Although the reduced encoding method is associated with lower signal-to-noise ratio (SNR) that impacts the quality of spectral analysis, the use of the parallel imaging method can lead to the same diagnostic outcomes as the fully sampled data when using the sensitivity-limited volumetric MRSI.
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Adolescents sustaining traumatic brain injury (TBI) show increased prevalence of behavior problems. This study investigated the associations of parent mental health, family functioning, and parent-adolescent interaction with adolescent externalizing behavior problems in the initial months after TBI, and examined whether injury severity moderated these associations. ⋯ Interventions targeting parent communication and/or improving caregiver psychological health may ameliorate potential externalizing behavior problems after adolescent TBI.
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Brain injury : [BI] · Jan 2014
Increased levels of interleukin-6, -8 and -10 are associated with fatal outcome following severe traumatic brain injury.
Despite the involvement of cytokine production in neurotrauma, there is still controversy regarding cytokines levels and clinical outcome following severe traumatic brain injury (TBI). ⋯ The findings indicate that increased IL-10, -8 and -6 levels may constitute an early predictor of unfavourable outcome in severe TBI patients.
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Brain injury : [BI] · Jan 2014
Identifying longitudinal trajectories of emotional distress symptoms 5 years after traumatic brain injury.
To evaluate longitudinal trajectories of emotional distress symptoms after traumatic brain injury (TBI). ⋯ Resilience was the most common trajectory following TBI. Patients characterized by recovery and chronic trajectories required attention and long-term clinical monitoring of their symptoms. Future research would benefit from longitudinal studies to analyse emotional distress symptoms and the strength of resilience over time.
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Pupillary dysfunction, a concerning finding in the neurologic examination of the patient with an acute traumatic brain injury often dictates the subsequent treatment paradigm. Patients were monitored closely with an infrared pupillometer, with NPi technology, for acute changes in pupillary function. NPi technology applies a scalar value to pupillary function. ⋯ A unilateral blown pupil and abnormal NPi score in a traumatic brain injury patient are not necessarily indicative of intracranial pressure issues, and must be correlated with the entire clinical scenario, to determine the etiology of the third nerve injury and direct potential therapeutic interventions. Early NPi score normalization suggests pupillary function may improve. We found that NPi scores, as a component of the clinical exam, provide a sensitive, noninvasive and quantitative means of following pupillary function acutely and chronically after a traumatic brain injury.