Articles: disease.
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To ascertain the annual incidence of diabetes requiring treatment with insulin in children and adolescents aged 0-19 years in Dar es Salaam, Tanzania, during a 10 year period from 1 January 1982 to 31 December 1991. ⋯ Juvenile diabetes mellitus is fairly rare in sub-Saharan Africa. If environmental factors such as infection and material deprivation were important determinants of insulin dependent diabetes in Africans, as they may be in Europeans, much higher rates would have been expected unless genetic factors possibly exert a protective role. The eightfold greater incidence in African Americans than in Tanzanians may be related to greater genetic admixture in African Americans with people from countries in Europe with a high incidence.
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Randomized Controlled Trial Clinical Trial
Are reminder stickers effective in reducing immunization dropout rates in Addis Ababa, Ethiopia?
A field trial to assess the effectiveness of a reminder sticker in reducing immunization dropout rates was conducted in two districts of Addis Ababa between 14 October 1991 and 31 January 1992. A total of 703 children were entered into the study. The study population was randomly divided into intervention and control groups. ⋯ This difference is clinically and statistically (P < 0.01) significant. Therefore, it is concluded that the reminder sticker is effective in reducing immunization dropout rates. Further investigations under operational conditions are recommended prior to the routine introduction of stickers into the immunization services.
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Historical Article
Evolution of paediatric oncology over the years: overview with a focus on sub-Saharan Africa and examples from the Kenyan experience.
In this paper on "The Evolution of Paediatric Oncology Over the Years", a historical perspective is outlined regarding the subspecialty of paediatric oncology on a global basis. The evolution of paediatric oncology units and their role in the progress of cancer management in children is highlighted. ⋯ The development of a paediatric oncology unit at the Kenyatta National Hospital in Nairobi, Kenya has been focused on, pointing out challenges, constraints and success that are associated in the initiation and nurturing of such units in developing countries. Lastly, Burkitt's lymphoma is singled out for discussion to illustrate problems that are abound in cancer management in children in sub-Saharan Africa.
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Mifepristone (RU 486) is an antiprogestin which interacts with progesterone at the receptor level. Administration of mifepristone immediately after ovulation does not upset the menstrual cycle. However, the maturation and function of the endometrium is inhibited and uterine contractility is changed. ⋯ On the basis of the time of the LH peak, it was retrospectively calculated that in 124 cycles at least one act of intercourse occurred during the period 3 days before to 1 day after ovulation. The probability of pregnancy in this period of the menstrual cycle is thus 0.008. The women did not complain of any treatment-related side-effects apart from slight bleeding for 2-3 days starting a few days after the day of treatment in 35% of the cycles.(ABSTRACT TRUNCATED AT 250 WORDS)