Articles: back-pain.
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Chronic pain affects ∼20% of the adult population and is associated with smoking. Smoking and pain worsen each other in the long term, but short-term temporal associations between smoking and pain throughout the day are unclear. Understanding these relationships may inform strategies for managing comorbid smoking and pain. ⋯ Further research is needed on interventions that combine tailored smoking cessation treatments and behavioral pain management strategies. PERSPECTIVE: This analysis of momentary data reported throughout the day by people with back pain who smoke revealed novel insights into short-term relationships between pain and smoking. Study results can inform future treatment development for individuals with chronic pain who smoke.
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Genome-wide association study (GWAS) meta-analysis with downstream analyses. ⋯ Level 3 (observational study).
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Lumbar disc herniation (LDH) with radiculopathy is associated with greater pain, disability, healthcare use, and costs compared with nonspecific low back pain. Reliable information about its incidence and risk factors were lacking. ⋯ Incidence of LDH varies in different populations and according to case definition. Risk factors include individual, behavioural, and work-related variables. Our findings support the need to develop standardised case definitions that validly classify the clinical spectrum of LDH and for future low risk of bias studies examining causal relationships for LDH with radiculopathy in adults.