Articles: postoperative-pain.
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Southern medical journal · Oct 1988
Postoperative ketamine analgesia in children: efficacy and safety after halothane anesthesia.
This study was done to investigate the effectiveness and safety of ketamine analgesia after halothane anesthesia for surgery in children. After completion of a surgical procedure, ten children had ketamine (1 mg/kg) injected intravenously during maintenance of anesthesia with 1% halothane in a 60:40 nitrous oxide-oxygen mixture. Cardiovascular parameters measured with noninvasive oscillometry and transthoracic impedance plethysmography remained unchanged after administration of ketamine. ⋯ When ketamine and halothane are administered in combination, careful restriction of dosages of these agents is recommended. Interaction of higher doses of ketamine and halothane has been reported to produce hypotension and bradycardia, which can be avoided with use of subdissociative, analgesic doses of ketamine during light halothane maintenance before emergence. After halothane anesthesia in healthy children, ketamine may be considered a suitable alternative to narcotics for postoperative analgesia.
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Randomized Controlled Trial Clinical Trial
Transcutaneous electrical nerve stimulation in the management of acute postoperative pain.
Twenty patients undergoing decompressive lumbar laminectomy were randomly allocated, in a double-blind manner, to receive active or inactive transcutaneous electrical nerve stimulation (TENS) as part of the management of their postoperative pain. All patients received the same non-narcotic general anaesthetic. The efficacy of the TENS was assessed by using a patient-controlled analgesia system (PRODAC) which delivered morphine i.v. ⋯ In addition, plasma morphine concentrations were measured hourly for the first 6 h and again at 24 h. There was no statistical difference between the two groups in the number of patient demands for analgesia, morphine dose or plasma morphine concentration. TENS offered no advantage over a placebo in the management of acute postoperative pain in these patients.
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Clinical Trial Controlled Clinical Trial
Patient-controlled analgesia versus intermittent analgesia dosing.
Actively involving the patient in his or her own pain management by using patient-controlled analgesia (PCA) during the postoperative period is a concept recently introduced. This method allows self-administration of small, frequent doses of an analgesic agent to maintain a state of constant pain control. We studied the relative efficacy of PCA compared with intermittent analgesic dosing in 16 male patients requiring posterolateral thoracotomy. ⋯ In the patients using PCA, a significant reduction in the postoperative pulmonary complication rate, as evidenced by radiographic findings, was noted. In addition, significantly less medication was used and postoperative fever was substantially reduced in the PCA group. We believe PCA to be a safe, effective, and beneficial pain management modality that deserves attention in the postoperative period.
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Randomized Controlled Trial Comparative Study Clinical Trial
Oral nalbuphine for the treatment of pain after dental extractions.
A randomized, double-blind comparison of nalbuphine 30 mg or 60 mg by mouth and dihydrocodeine 30 mg by mouth was conducted in 75 patients with moderate to severe pain after surgery for dental extractions under general anaesthesia. A significant reduction in pain intensity followed each treatment and persisted throughout the 4-h observation period after nalbuphine, but only for 3 h after dihydrocodeine was given. ⋯ However, the patients who received nalbuphine 30 mg had a significantly higher mean pain intensity before treatment than those in the other groups. The side-effects encountered were those typical of opioid medication; there were no statistically significant differences between the groups.