Articles: postoperative-pain.
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Acta Anaesthesiol Scand · Oct 1982
Randomized Controlled Trial Comparative Study Clinical TrialPostoperative analgesia and lung function: a comparison of intramuscular with epidural morphine.
Thirty healthy patients subjected to cholecystectomy or operation for duodenal ulcer were allocated randomly for postoperative analgesic treatment with morphine i.m. or epidurally. Morphine was given only at the request of the patients and only as much was given as was needed to obtain satisfactory pain relief. ⋯ Compared with the i.m. group, there was a higher arterial oxygen tension and a slower increase in alveolar-arterial oxygen difference. It is concluded that epidural morphine analgesia reduces the degree of postoperative lung dysfunction compared with conventional i.m. morphine treatment.
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Br J Clin Pharmacol · Oct 1982
Randomized Controlled Trial Clinical TrialCodeine added to paracetamol induced adverse effects but did not increase analgesia.
1 In a double-blind crossover study identical oral surgical procedures were performed on two separate occasions in 24 outpatients. 2 At one operation they were given tablets containing paracetamol + codeine phosphate (400 mg + 30 mg), and at the other plain paracetamol (400 mg). The day of operation 2 tablets were taken 3, 6 and 9 h after surgery, the following two days 1 tablet four times daily. 3 Several measurements/assessments were recorded for a paired comparison of the postoperative courses. 4 No increase In the analgesic effect could be demonstrated by addition of codeine to paracetamol. 5 On the day of operation 18 patients reported adverse effects like nausea, dizziness and drowsiness with paracetamol + codeine, while only 3 patients experienced side effects with paracetamol alone (P less than 0.001). 6 Measurements revealed almost identical swelling after the two operations. 7 Compared with results obtained in previous studies, the present findings indicate that paracetamol may exert anti-inflammatory activity and reduce postoperative swelling, even when given 3 h after surgery. 8 On the day of operation and the following two days 20 patients preferred the treatment with plain paracetamol, while only 4 favoured paracetamol + codeine (P less than 0.001).
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Randomized Controlled Trial Comparative Study Clinical Trial
Caudal block for postoperative analgesia in children.
A clinical trial was performed to compare the effects of intramuscular dihydrocodeine with caudal bupivacaine on postoperative pain and recovery in 181 children who had undergone either circumcision, inguinal herniotomy or orchidopexy performed under general anaesthesia. Linear analogues were used in assess level of consciousness and apparent pain. Recovery of consciousness was slower after caudal analgesia. For 90 minutes following circumcision there was significantly less pain and caudal analgesia, but better pain relief could not be demonstrated following inguinal herniotomy and orchidopexy.
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Randomized Controlled Trial Comparative Study Clinical Trial
Zomepirac, placebo and paracetamol/dextropropoxyphene combination compared in orthopaedic postoperative pain.
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Methods available for the relief of postoperative pain are reviewed. The use of intermittent injections of morphine is likely to remain the established method and suggestions are made for its more effective use. Newer methods are discussed in terms of their expense and the effects on medical and nursing workload. It is suggested that nurses trained in pain relief methods could greatly improve the relief of pain following operation.