Articles: low-back-pain.
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Observational Study
Swiss chiropractic cohort (Swiss ChiCo) pilot study: feasibility for a musculoskeletal cohort study conducted within a nationwide practice-based research network.
Practice-based research networks are collaborations between clinicians and researchers to advance primary care research. This study aims to assess the feasibility for longitudinal data collection within a newly established chiropractic PBRN in Switzerland. ⋯ The Swiss ChiCo pilot study exceeded its prespecified feasibility objectives. Nationwide longitudinal data capture was highly feasible. Similar to other practice-based cohorts, participant retention remains a challenge. Trial registration Swiss chiropractic cohort (Swiss ChiCo) pilot study (ClinicalTrials.gov identifier: NCT05116020).
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To understand lumbosacral transitional vertebra (LSTV)-associated degenerative pathologies and their correlation to low back pain and radicular pain. ⋯ Patients with low back pain had a higher incidence of sacralization with corresponding disc degeneration, facet tropism ,and end plate changes. In patients with radicular pain, lumbarization was associated only with facet tropism. These findings may aid clinicians in prognostication and patient counseling.
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Vertebral endplate lesions (EPLs) caused by severe disk degeneration are associated with low back pain. However, its pathophysiology remains unclear. In this study, we aimed to develop a vertebral EPL rat model mimicking severe intervertebral disk (IVD) degeneration by injecting monosodium iodoacetate (MIA) into the IVDs and evaluating it by assessing pain-related behavior, micro-computed tomography (CT) findings, and histological changes. ⋯ Our rat EPL model showed progressive morphological vertebral endplate changes in a time- and concentration-dependent manner, similar to the degenerative changes in human IVDs. This model can be used as an animal model of severe IVD degeneration to better understand the pathophysiology of EPL.
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Background There are concerns over the reliability and comprehensibility of health-related information on the internet. We analyzed the readability, reliability and quality of online patient education materials obtained from websites associated with chronic low back pain (cLBP). Methods On 26 April 2022, the term 'cLBP' was used to perform a search on Google, and 95 eligible websites were identified. ⋯ Websites of different typologies were found to significantly differ in their reliability and the quality scores (p<0.05). Conclusion The reading ability required for cLBP-related information on the internet was found to be considerably higher than that recommended by the National Health Institute and had low reliability and poor quality. We believe that online information should have readability appropriate for most readers and must have reliable content that is appropriate to educate the public, particularly for websites that provide patient education material.