Articles: general-anesthesia.
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Minerva anestesiologica · Jul 1995
Clinical Trial[Mechanical ventilation with laryngeal mask in anesthesia. Personal experience].
The aim of the study was to evaluate the following: the difficulty of inserting a laryngeal mask without the use of muscle relaxants and laryngoscopy; the incidence of possible intraoperative cardiocirculatory and respiratory alterations during the association of laryngeal mask and mechanical ventilation; local intra and postoperative complications due to their combined use. ⋯ There was no difficulty in positioning the laryngeal mask without muscle relaxants and laryngoscopy; no alterations were observed in the hemodynamic and respiratory parameters monitored; intra and postoperative local complications were frequently present in a high percentage of cases, consisting respectively in increased mucopharyngeal secretion and pharyngeal irritation and dysarthria. Whereas the former did not represent a serious clinical problem, the latter proved more troublesome for patients following surgery.
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Anesthesia and analgesia · Jul 1995
Randomized Controlled Trial Clinical TrialIntravenous ketorolac tromethamine does not worsen platelet function during knee arthroscopy under general anesthesia.
Ketorolac (KT) prolongs bleeding time and inhibits platelet aggregation and platelet thromboxane production in healthy, awake volunteers. However, platelet function may be accentuated during the stress of general anesthesia (GA) and surgery. The purpose of this study was to investigate platelet function changes during a standard GA technique and surgery, as well as after a single intraoperative dose of intravenous (i.v.) KT. ⋯ Platelet function appears to be accentuated during GA and surgery as evaluated by BT in the placebo group. Further, platelet function by BT, PA, and TEG was not inhibited after i.v. KT despite near complete abolition of TxB2 production.
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Multichannel laser Doppler flowmeters allow continuous, simultaneous measurement of perfusion in several organs. We measured microcirculatory blood flow in the kidney, liver, skin and skeletal muscle in 10 anaesthetized rats subjected to abdominal surgery and graded haemorrhage (withdrawal of 5% total blood volume every 10 min). Mean arterial blood pressure, heart rate and haemoglobin concentrations were also measured. ⋯ We conclude that laser Doppler flowmetry is useful for continuous measurement of microcirculatory blood flow in several organs simultaneously during haemorrhagic hypovolaemia. It showed that microcirculatory blood flow in skeletal muscle is particularly sensitive to lesser degrees of blood loss during anaesthesia. Hypovolaemia-induced slow wave flowmotion occurred only in skeletal muscle, which may be linked to fluid mobilization during haemorrhage.