Articles: general-anesthesia.
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Anesthesia and analgesia · Jul 1995
Randomized Controlled Trial Clinical TrialIntravenous ketorolac tromethamine does not worsen platelet function during knee arthroscopy under general anesthesia.
Ketorolac (KT) prolongs bleeding time and inhibits platelet aggregation and platelet thromboxane production in healthy, awake volunteers. However, platelet function may be accentuated during the stress of general anesthesia (GA) and surgery. The purpose of this study was to investigate platelet function changes during a standard GA technique and surgery, as well as after a single intraoperative dose of intravenous (i.v.) KT. ⋯ Platelet function appears to be accentuated during GA and surgery as evaluated by BT in the placebo group. Further, platelet function by BT, PA, and TEG was not inhibited after i.v. KT despite near complete abolition of TxB2 production.
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Minerva anestesiologica · Jul 1995
Clinical Trial[Mechanical ventilation with laryngeal mask in anesthesia. Personal experience].
The aim of the study was to evaluate the following: the difficulty of inserting a laryngeal mask without the use of muscle relaxants and laryngoscopy; the incidence of possible intraoperative cardiocirculatory and respiratory alterations during the association of laryngeal mask and mechanical ventilation; local intra and postoperative complications due to their combined use. ⋯ There was no difficulty in positioning the laryngeal mask without muscle relaxants and laryngoscopy; no alterations were observed in the hemodynamic and respiratory parameters monitored; intra and postoperative local complications were frequently present in a high percentage of cases, consisting respectively in increased mucopharyngeal secretion and pharyngeal irritation and dysarthria. Whereas the former did not represent a serious clinical problem, the latter proved more troublesome for patients following surgery.
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During surgery, the anesthesiologists adjust the concentration of inhaled anesthetics according to the change in blood pressure in order to achieve good control of anesthesia. Usually the thinking patterns of individual anesthesiologists differ from one to another. ⋯ The results showed that anesthesiologists' regulation rules were formed independently of the 3 drugs and were specific to individuals. Some trends depending on institution were observed, but no statistically significant difference was found.
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Case Reports
Combined orthotopic liver transplantation and caesarean section for the Budd-Chiari syndrome.
Fulminant hepatic failure is a rare complication of pregnancy. We describe a case of Budd-Chiari syndrome that resulted in the need for combined liver transplantation and Caesarean section at 32 weeks' gestation. The anaesthetic and perioperative management are discussed.