Articles: general-anesthesia.
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Gastric pH values were studied prior to, and up to, ninety minutes after an intravenous injection of cimetidine 200 mg given before general anaesthesia, in twenty surgical patients, all with a gastric pH less than 3.5. At thirty, sixty and ninety minutes, sixteen, eighteen and twenty patients had a gastric pH greater than 3.5 respectively. In conclusion, the results of the present study indicate that cimetidine 200 mg given intravenously 90 minutes before surgery will reduce the hazard of chemical pneumonitis should stomach content be aspirated.
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The morbidity of transplantation is considerably decreased and the mortality of cadaver transplants from sepsis has been reduced to 5% or less as the result of excessive immunosuppression therapy and reduced infection. There is uniform agreement that renal transplantation has the best potential for restoring a patient with end-stage renal failure to his normal state of physical, mental, and psycho-social health. Both regional and general anesthesia have their drawbacks in kidney transplants. However, by combining the practice of safe anesthesia, improved surgical techniques, and better knowledge of the immunosuppressant drugs, there is near perfect control over the possibility of kidney rejection in kidney transplantation between identical twins.
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Nippon Sanka Fujinka Gakkai Zasshi · Apr 1983
[The maternal and fetal acid-base status during general or spinal anesthesia for elective cesarean section in the left tilt position].
Thirty one healthy parturients received spinal or general anesthesia for elective cesarean section. Maternal blood pressures, maternal and fetal acid-base values, induction to delivery intervals (I-DI) and Apgar scores were determined. On spinal anesthesia, acute hydration by 6% hydroxyethyl starch solution and intramuscular injection of ephedrine were enforced prior to the block and in the left tilt position (17 degrees) oxygen inhalation immediately after the block was begun (group OII: 16 cases). ⋯ A positive correlation between umbilical venous pH values and 1 or 5 minutes Apgar scores was confirmed in group OII, and a negative correlation between 1 minute Apgar scores and I-DI was noticed in group G. Fetal acid-base values were not correlated with I-DI in either group, and it was postulated that placental or fetal circulation was sufficiently maintained. Biochemical status and clinical conditions in mothers and their infants are very favorable in well-conducted general or spinal anesthesia for elective cesarean section.