Articles: neuralgia.
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Arch Neurol Chicago · Oct 1993
Topical aspirin in chloroform and the relief of pain due to herpes zoster and postherpetic neuralgia.
To determine pain patterns and relationships in patients with herpes zoster and postherpetic neuralgia before and after topical application of aspirin dissolved in chloroform applied to the painful skin surface. ⋯ Topical aspirin dissolved in chloroform is an effective means of reducing pain due to herpes zoster and postherpetic neuralgia in most patients. The locus of pain origin and analgesia induced by topical aspirin is most likely at cutaneous free-nerve ending pain receptors. The mechanism responsible for the analgesic properties of aspirin is probably not the same as that responsible for its anti-inflammatory properties.
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Fortschritte der Medizin · Sep 1993
Case Reports[Oral combination therapy of zoster neuralgia. Pain reduction by 1-adamantanamine sulfate and carbamazepine per os].
In four patients hospitalized with severe neuralgic complaints in conjunction with a Zoster infection, the pain-relieving effect of oral 1-adamantanamine sulfate used in combination with carbamazepine was studied. From the results obtained, the oral administration of 1-adamantanamine sulfate also appears to have a reliable analgesic effect, so that ambulatory treatment is readily possible.
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We report the case of a 65 year old man who has been suffering from segmental back pain for 10 years. The diagnosis postherpetic neuralgia following herpes zoster sine herpete was fixed 9 years after the beginning of pain. All treatments prior to ours were ineffective. Acupuncture and the use of homeopathic drugs led to success at last.
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Neurogenic pain (encompassing all types of neuropathic and central pain) is discussed. Experimental work is presented in a model in which the rat sciatic nerve is loosely ligatured. In painful human neuropathies, tricyclic antidepressants have been found to be effective in proportion to the degree they facilitate monoaminergic activity. ⋯ In nociceptive pain, recent findings in humans emphasize the importance of both the retroinsular (SII) and the anterior cingulate cortices in the conscious appreciation of pain. Opioid studies have revealed individual differences in the metabolism of morphine to its 3- and 6-glucuronosides; patients with nociceptive pain who respond poorly to morphine or diamorphine probably have a high 3:6 ratio. It has been pointed out that methadone may be useful in such cases, as it is not broken down to glucuronosides.
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Clin Neurol Neurosurg · Jan 1993
Brachial plexus injury: deafferentation pain and dorsal root entry zone (DREZ) coagulation.
The nature of deafferentation pain in cases of brachial plexus injury is described. The natural course of the symptoms together with conservative treatment is outlined. The theoretical background of the dorsal root entry zone (DREZ) coagulation, and its clinical indications, operative techniques and results are presented.