Articles: intubation.
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Randomized Controlled Trial Clinical Trial
Bolus doses of esmolol for the prevention of perioperative hypertension and tachycardia.
The effectiveness of esmolol, an ultra short-acting cardioselective beta blocker, in the prevention and treatment of post-intubation haemodynamic perturbations, was investigated. Forty-eight ASA physical status I and II patients undergoing hysterectomy were randomly assigned to receive a single intravenous bolus of placebo, esmolol 100 mg, or esmolol 200 mg in a double-blind fashion. This was administered over 15 sec, and immediately followed by thiopentone 3-5 mg.kg-1, succinylcholine 1.5 mg.kg-1, and tracheal intubation 90 sec later. ⋯ The systolic blood pressure post-induction was lower in the esmolol 200 mg group (P less than 0.05); following intubation, however, no significant differences were seen among groups in systolic, diastolic, or mean blood pressures. Following tracheal intubation, the incidence of ventricular arrhythmias was lower in the esmolol groups (P less than 0.05). In summary, esmolol in 100 mg and 200 mg doses was effective in mitigating the haemodynamic response following tracheal intubation.
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Comment Letter Case Reports
The length of the blade is more important than its design in difficult tracheal intubation.
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Securing an endotracheal tube on patients with facial burns or trauma can pose difficulties. A nasotracheal support splint, made of materials commonly used by occupational therapists, can facilitate safe anchoring of a nasotracheal tube.
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J Burn Care Rehabil · Mar 1990
Smoke inhalation and airway management at a regional burn unit: 1974 to 1983. II. Airway management.
According to criteria established to define patients with smoke inhalation, the airway management of all victims of smoke and burns (1974 to 1984; n = 805) was reviewed. Fourteen percent of all patients were intubated (n = 117); patients intubated on the day of injury (n = 41) were more likely to extubate themselves or have technical problems with the endotracheal tube. Twelve percent of patients with smoke inhalation without burns required endotracheal intubation versus 62% of those with burns. ⋯ The prolonged length of stay for patients with a tracheotomy relates to the severity of the burn. Tracheotomy was not the cause of death in any patient. The strategy of grafting the neck before tracheotomy was used successfully in eight patients.
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Aspiration of gastric contents continues to be one of the most serious complications of general anesthesia. Laryngeal competence may be reduced immediately following endotracheal extubation, which may increase the risk of aspiration. ⋯ Evaluation of radiographs from both groups revealed that no aspirate of barium was detected in the tracheobronchial trees of any of the dogs. This study establishes that there is no difference in the risk of aspiration following endotracheal extubation using the canine model regardless of the clinical technique employed.