Articles: acute-pain.
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Observational Study
Predicting Acute Pain After Surgery: A Multivariate Analysis.
To identify perioperative practice patterns that predictably impact postoperative pain. ⋯ The presented analysis offers detailed insight into current practice patterns and reveals modifications that can be implemented in today's clinical practice. Our results also suggest that parameters other than those currently studied are relevant for postoperative pain including biological and psychological variables.
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Reg Anesth Pain Med · Feb 2021
Observational StudyInfluence of inpatient opioid consumption on persistent use following total knee arthroplasty.
Total knee arthroplasty (TKA) is associated with a high incidence of continued opioid use beyond the expected period of recovery. The aim of this study was to determine the influence of inpatient opioid consumption on the development of persistent use. ⋯ Larger amounts of opioid consumed in the hospital following uncomplicated, primary TKA may not be associated with an increased risk of persistent use at 6 weeks among opioid-naïve patients. Patients may have unique risk factors for prolonged opioid use that may not necessarily be apparent in the early postoperative period.
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Randomized Controlled Trial
Rapid Administration of Methoxyflurane to Patients in the Emergency Department (RAMPED) Study: A Randomised controlled trial of Methoxyflurane vs Standard care.
The objective was to evaluate the effectiveness of methoxyflurane versus standard care for the initial management of severe pain among adult emergency department (ED) patients. ⋯ Initial management with inhaled methoxyflurane in the ED did not achieve the prespecified substantial reduction in pain, but was associated with clinically significant lower pain scores compared to standard therapy.