Articles: sepsis.
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Southern medical journal · Feb 1977
Case ReportsFatal sepsis associated with an intrauterine device and pregnancy.
The 15th case of maternal death associated with sepsis in pregnancy in a patient using the Dalkon Shield intrauterine device is reported. Intrauterine sepsis appears to be a complication of the use of this device. ⋯ The management of sepsis during pregnancy associated with an in situ IUD often requires a combined medical and obstetrical approach. The removal of all Dalkon Shields is strongly recomended.
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When albino mice with experimental staphylococcal sepsis were treated by doxycycline for 10 days, it was noted that the antibiotic had an inhibitory effect on the absorbing capacity of the peritoneal leucocytes with respect to Staph aureus. The decreased digesting capacity of the leucocytes was observed only during the first 5 days from the moment of infection and treatment. The combined use of doxycycline and pentoxyl stimulated the activity and intensity of phagocytosis. The activity values of completed phagocytosis did not change, while the coefficient of the phagocytosis completeness increased as compared to the same values in the animal group treated with doxycycline alone.