Articles: critical-care.
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Critical care
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Case Reports
Ketamine infusion. Its use as a sedative, inotrope and bronchodilator in a critically ill patient.
A patient with acute lymphatic leukaemia developed a bilateral fulminating Pseudomonas aeruginosa pneumonia and required controlled ventilation of the lungs. Marked agitation, hypotension and bronchospasm unresponsive to conventional bronchodilators presented a therapeutic challenge. ⋯ The clinical improvement was maintained for the 5 days during which ketamine was infused. Plasma concentrations of ketamine and its metabolites are reported.