Articles: pain.
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The time from the end of surgery to the administration of the first post-operative analgesic has been measured in 86 patients following brachial plexus block with bupivacaine, lignocaine, nepivacaine or prilocaine. A signficant increase in time occurred with bupivacaine; the combination of regional and general anesthesia significantly increased the time when compared with general anaesthesia in the same patient. In children, the use of regional anaesthesia almost removed the need for analgesia after surgery.
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The Journal of urology · Apr 1978
Case Reports Comparative StudyChemical hypophysectomy for relief of bone pain in carcinoma of the prostate.
A series is presented of 10 patients with intractable pain secondary to diffuse metastatic prostatic carcinoma. These patients underwent pituitary ablation by a new method of chemical hypophysectomy, which consisted of multiple injections of absolute alcohol into the pituitary gland under stereotaxic control. ⋯ The sequelae are those associated with pituitary destruction, the most significant being diabetes insipidus. Preoperative and postoperative hormonal studies failed to reveal any significant hormonal changes despite good and almost immediate pain relief.
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Thresholds of non-painful and painful perception for electrical stimuli are not altered significantly during dorsal column stimulation either in the area of induced paresthesia or outside it. After long term stimulation of the dorsal column the thresholds for stimuli are significantly higher within the area of induced paresthesia but not outside it. Median nerve evoked somatosensory cortical potentials are not altered by conditioning or simultaneous DC stimulation. During DCS in three of eight patients only the vibration evoked cortical potentials were attenuated in the early three components of the potential.