Articles: critical-illness.
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Hypophosphatemia has been reported after refeeding of malnourished patients. Nutritional support is often delayed in patients in the intensive care unit (ICU) as a consequence of enteral intolerance and bowel hypomotility. ⋯ Refeeding hypophosphatemia occurs commonly in critically ill patients in the ICU. Starvation for a period as short as 48 hours and poor nutritional status predispose to this syndrome. Patients at risk should be refed slowly, and the serum phosphorus level should be closely monitored and supplemented as required.
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Randomized Controlled Trial Comparative Study Clinical Trial
A double-blind, prospective, randomized study of glutamine-enriched compared with standard peptide-based feeding in critically ill patients.
Arterial and venous plasma amino acids were determined in 28 intensive care patients randomly assigned to receive 10 d of isoenergetic, isonitrogenous feedings that differed sixfold in glutamine content. Subjects were generally well-matched for age, injury severity, and disease diagnoses. Nasojejunal feedings were started within 48 h of admission. ⋯ There were, however, significant (P < 0.05) increases in arterial or venous plasma total, indispensable, and branched-chain amino acids of 125-144% by day 5 only in patients fed the standard control diet. The phenylalanine-tyrosine ratio was elevated on day 1 in both groups (1.3-1.4) but decreased significantly only in the glutamine-supplemented group (1.1 compared with 1.4) by day 5. Glutamine supplementation blunted the hyperaminoacidemia and elevated aromatic amino acid response to injury.
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Intensive care medicine · Oct 1996
Validation of a quality of life questionnaire for critically ill patients.
Development and validation of quality of life questionnaire for critical care patients. ⋯ Questionnaire meets objectives recommended for critical care use, and fulfills essential requirements of validity and reproducibility when applied to critically ill patients.