Articles: anesthetics.
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Randomized Controlled Trial Multicenter Study
Comparison of adequacy of anaesthesia monitoring with standard clinical practice monitoring during routine general anaesthesia: An international, multicentre, single-blinded randomised controlled trial.
Previous studies have suggested that monitoring the levels of both hypnosis and antinociception could reduce periods of inadequate anaesthesia. However, the evidence regarding associated benefits of this monitoring is still limited. ⋯ In the current study, the guidance of total intravenous anaesthesia by Entropy and surgical pleth index in comparison with standard monitoring alone was not able to validate reduction of unwanted anaesthesia events. However, there was a reduction in the use of propofol, and shorter times for emergence and time spent in the postanaesthesia care unit.
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Anesthesia and analgesia · Dec 2020
Randomized Controlled Trial Multicenter StudyTransversus Abdominis Plane Block With Liposomal Bupivacaine for Pain After Cesarean Delivery in a Multicenter, Randomized, Double-Blind, Controlled Trial.
Transversus abdominis plane block with liposomal bupivacaine improved post-caesarean section analgesia when used as part of a multimodal analgesia protocol.
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Prehosp Disaster Med · Dec 2020
Multicenter StudyRescue Intubation in the Emergency Department After Prehospital Ketamine Administration for Agitation.
Prehospital intramuscular (IM) ketamine is increasingly used for chemical restraint of agitated patients. However, few studies have assessed emergency department (ED) follow-up of patients receiving prehospital ketamine for this indication, with previous reports suggesting a high rate of post-administration intubation. This study examines the rate of and reasons for intubation and other airway interventions in agitated patients who received ketamine by Emergency Medical Services (EMS). ⋯ The observed rate of intubation in patients receiving prehospital ketamine for agitation was 16.3%. Study data did not reveal an age or dose-dependent rate of intubation. Further research should be conducted to compare the airway intervention rate of agitated patients receiving ketamine versus other sedatives in a controlled fashion.
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Minerva anestesiologica · Oct 2020
Multicenter Study Meta AnalysisEffect of volatile anesthetics on mortality and clinical outcomes in patients undergoing coronary artery bypass grafting: a meta-analysis of randomized clinical trials.
For patients undergoing coronary artery bypass grafting there is no mortality difference between volatile anaesthesia and TIVA.
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Randomized Controlled Trial Multicenter Study
Anesthesia and Circulating Tumor Cells in Primary Breast Cancer Patients: A Randomized Controlled Trial.
Type of maintenance anesthesia, whether propofol or sevoflurane, had no effect on circulating tumor cell count after primary breast cancer surgery.
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