Articles: brain-injuries.
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Seventeen patients with posterior fossa extradural haematoma are presented. While 7 patients had acute course, 6 had subacute and 4 had chronic course. All patients had evidence of occipital injury. ⋯ All patients with subacute and chronic course had good outcome while 43% with acute course succumbed to death. Besides the initial clinical status the co-existing lesions signifying the increased severity of injury have influenced the mortality and quality of outcome. In presence of occipital fracture a careful observation and timely intervention are warranted.
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Intensive care medicine · Jul 1995
Randomized Controlled Trial Comparative Study Clinical TrialGastric emptying following brain injury: effects of choice of sedation and intracranial pressure.
To compare the effects of opioid and non-opioid sedation on gastric emptying. ⋯ Gastric emptying is not improved in patients with brain injury by avoiding morphine (1-8 mg/h) in the sedative regimen. Intracranial hypertension is associated with reduced gastric emptying.
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Comparative Study
Reduction of post-traumatic intracranial hypertension by hypertonic/hyperoncotic saline/dextran and hypertonic mannitol.
Cerebral injury is seen in one of three patients with multiple traumas; thus efficient shock treatment is a most important measure against the development of secondary brain damage. Small-volume resuscitation in severe hemorrhagic shock by hypertonic/hyperoncotic saline/dextran has been shown to instantaneously normalize cardiac output and to raise systemic blood pressure. In this study, the fluid regimen was compared with hypertonic mannitol to investigate their therapeutic efficacy in intracranial hypertension. ⋯ The increase of the cerebral water content of the traumatized hemisphere was associated with a respective increase of the cerebral Na+ content and a (nonsignificant) decrease of the K+ content. The present findings demonstrate that the hypertonic/hyperoncotic saline/dextran was as efficient as the mannitol in reducing ICP that had been increased by a cerebral lesion and a space-occupying mass; the underlying mechanisms responsible for the reduction might differ. Because of the powerful hemodynamic properties of the saline/dextran in circulatory shock, administration of the solution in patients with multiple traumas and head injury might be particularly advantageous for the prevention of secondary ischemic brain damage.
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To report updated national trends in traumatic brain injury deaths from 1979 through 1992. ⋯ These data highlight the success of efforts to prevent traumatic brain injury due to motor vehicles and failure to prevent such injuries due to firearms. The increasing importance of penetrating injury has important implications for research, treatment, and prevention of traumatic brain injury in the United States.