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pearl
1
Use of propofol for ambulatory surgery results in less post-operative nausea and vomiting, though no difference in post-discharge nausea and vomiting, and with greater cost compared with volatiles.
Kumar G, Stendall C, Mistry R et al. A comparison of total intravenous anaesthesia using propofol with sevoflurane or desflurane in ambulatory surgery: systematic review and meta-analysis. Anaesthesia. 2014 Oct 1; 69 (10): 1138-50.
  Daniel Jolley
pearl
1
Spinal anesthesia for neonatal hernia repair reduces the incidence of early post-operative apnea but has no effect on later apnea (30 min to 12 hours).
Davidson AJ, Morton NS, Arnup SJ et al. Apnea after Awake Regional and General Anesthesia in Infants: The General Anesthesia Compared to Spinal Anesthesia Study-Comparing Apnea and Neurodevelopmental Outcomes, A Randomized Controlled Trial. Anesthesiology. 2015 Jul 1; 123 (1): 38-54.
  Daniel Jolley
pearl
1
Use of ultrasound guidance for subclavian vein cannulation reduces the incidence of arterial puncture, pneumothorax, and hematoma.
Lalu MM, Fayad A, Ahmed O et al. Ultrasound-Guided Subclavian Vein Catheterization: A Systematic Review and Metaanalysis. Crit. Care Med. 2015 Jul 1; 43 (7): 1498-507.
  Daniel Jolley
pearl
1
Measuring B-type natriuretic peptides post-operatively improves risk stratification in patients undergoing non-cardiac surgery.
Rodseth RN, Biccard BM, Le Y et al. The prognostic value of pre-operative and post-operative B-type natriuretic peptides in patients undergoing noncardiac surgery: B-type natriuretic peptide and N-terminal fragment of pro-B-type natriuretic peptide: a systematic review and individual patient data meta-analysis. J. Am. Coll. Cardiol. 2014 Jan 21;63(2):170-80.
  Daniel Jolley
pearl
1
Sevoflurane-based anesthesia is associated with a similar incidence of myocardial ischema as for propofol-based anesthesia.
Lurati GA, Schumacher P, Seeberger E et al. Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery. Circulation. 2012 Dec 4;126(23):2696-704.
  Daniel Jolley
summary
1
This retrospective audit could find no difference in either cancer recurrence or median survival between patients receiving an epidural versus those who did not for analgesic management of total or partial gastrectomy.
Cummings KC, Patel M, Htoo PT et al. A Comparison of the Effects of Epidural Analgesia Versus Traditional Pain Management on Outcomes After Gastric Cancer Resection: A Population-Based Study. Reg Anesth Pain Med. 2014 May 1; 39 (3): 200-7.
  Daniel Jolley
pearl
1
General anesthesia has only small effects on myocardial perfusion in healthy patients.
Bulte CS, Boer C, Loer SA. Perioperative myocardial perfusion: an anesthesiologists' concern? Curr Opin Anaesthesiol. 2015 Feb 1;28(1):101-6.
  Daniel Jolley
pearl
1
Wound infiltration with ropivacaine offers no analgesic benefit after thyroid surgery.
Miu M, Royer C, Gaillat C et al. Lack of Analgesic Effect Induced by Ropivacaine Wound Infiltration in Thyroid Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial. Anesth. Analg. 2016 Feb 1; 122 (2): 559-64.
  Daniel Jolley
pearl
1
High-normal fasting plasma glucose (95-99 mg/dL 5.3−5.5 mmol/L) is independently associated with increased cardiovascular risk compared with low-normal FPG (< 80 mg/dL / 4.44 mmol/L).
Shaye K, Amir T, Shlomo S et al. Fasting glucose levels within the high normal range predict cardiovascular outcome. Am. Heart J. 2012 Jul 1;164(1):111-6.
  Daniel Jolley
pearl
1
Alphaxalone may be solubilized in a sulfobutyl-cyclodextrin with potency comparable to both propofol and the historical Cremophor EL preparation, but with a better safety margin than either.
Goodchild CS, Serrao JM, Kolosov A et al. Alphaxalone Reformulated: A Water-Soluble Intravenous Anesthetic Preparation in Sulfobutyl-Ether-β-Cyclodextrin. Anesth. Analg. 2015 May 1; 120 (5): 1025-1031.
  Daniel Jolley