• Arch Iran Med · Oct 2019

    Prevalence of Autism and its Comorbidities and the Relationship with Maternal Psychopathology: A National Population-Based Study.

    • Mohammad Reza Mohammadi, Nastaran Ahmadi, Ali Khaleghi, Hadi Zarafshan, Seyed-Ali Mostafavi, Koorosh Kamali, Mehdi Rahgozar, Ameneh Ahmadi, Zahra Hooshyari, Seyyed Salman Alavi, Alia Shakiba, Maryam Salmanian, Parviz Molavi, Nasrin Sarraf, Seyed Kaveh Hojjat, Soleiman Mohammadzadeh, Shahrokh Amiri, Soroor Arman, and Ahmad Ghanizadeh.
    • Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
    • Arch Iran Med. 2019 Oct 1; 22 (10): 546-553.

    BackgroundThere is no clear picture regarding the prevalence rates of autism and its comorbidities among Iranian children and adolescents. The present study aimed to estimate these rates as part of a large national population-based study on epidemiology of psychiatric disorders in Iranian children and adolescents.MethodsThe total sample consisted of 31000 children and adolescents between 6 to 18 years of age. The Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Present and Life time version (K-SADS-PL) was used as the diagnostic tool.ResultsThe prevalence of autism in the total sample is equal to 0.1% (10 per 10000), with a 2:1 male-to-female ratio. In total, 86% of people with autism had at least one comorbid condition. Intellectual disability, epilepsy, enuresis and attention deficit and hyperactivity disorder (ADHD) with prevalence rates of 70.3%, 29.7%, 27% and 21.62%, respectively, were the most prevalent comorbid conditions in people with autism. Maternal personality disorders were also shown to be associated with increasing risk of autism.ConclusionThe present study shows high prevalence rates for autism and its comorbid conditions among Iranian children and adolescents. It also reveals that there is a relationship between some maternal psychiatric disorders and the risk of autism.© 2019 The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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