• Brit J Hosp Med · May 2020

    Review

    An overview of study designs.

    • Julian Aquilina, Joana B Neves, and Maxine Gb Tran.
    • Faculty of Medical Sciences, University College London, London, UK.
    • Brit J Hosp Med. 2020 May 2; 81 (5): 1-6.

    AbstractThe numbers of clinical trials have increased exponentially over the last decade, amplifying the pressure to select an appropriate study design to obtain reliable and valid evidence. The ability to find, critically appraise and use evidence to develop new interventions is fundamental to evidence-based medicine. Different study designs have their own advantages and disadvantages, and provide different evidentiary value. This article provides an overview of clinical trials, illustrating that, ultimately, the study design chosen needs to meet experimental and funding limitations, while minimising error.

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