• Clin Med (Lond) · Nov 2019

    Case Reports

    Ovarian cyst haemorrhage as a complication of acute myelomonocytic leukaemia induction therapy.

    • Amy L Irwin, Katherine Smith, and Nigel Sargant.
    • North Hampshire and Basingstoke Hospital, Basingstoke, UK amy.irwin@hhft.nhs.uk.
    • Clin Med (Lond). 2019 Nov 1; 19 (6): 509510509-510.

    BackgroundHere we present a case of acute ovarian cyst haemorrhage in a young female during induction therapy for acute myelomonocytic leukaemia (AMML).Case PresentationA patient undergoing chemotherapy on the AML19 trial for AMML developed severe abdominal pain and haemodynamic compromise during cycle 2 of fludarabine, cytarabine and idarubicin. The patient was found to have a large ruptured haemorrhagic ovarian cyst on computed tomography. She was managed conservatively due to relative haematological contraindications to surgery and haemodynamic stability following transfer to the high dependency unit. The patient had recently discontinued anticoagulation for pulmonary emboli due to thrombocytopenia.ConclusionsThis highlights the importance of recognising coexistent pathology in patients undergoing high intensity chemotherapy.© 2019 Royal College of Physicians.

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