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Case Reports
Lessons of the month 3: Gone but not forgotten - Osler - a reminder of the syndrome not bearing his name.
- Amit Kj Mandal, Bashir Mohamad, and Constantinos G Missouris.
- Wrexham Park Hospital, Slough, UK.
- Clin Med (Lond). 2019 Nov 1; 19 (6): 523525523-525.
AbstractStreptococcus pneumoniae is the most frequently implicated microbial agent in community acquired bacterial pneumonia and meningitis. It is also responsible for between 1 and 3% of cases of native valve infective endocarditis, with mortality rates up to 60%. Osler first described the association between pneumococcal pneumonia, endocarditis, and meningitis secondary to bacteria that he described as 'micrococci', subsequently elucidated to be S pneumoniae by Robert Austrian, and the syndrome bears his name. We report a case of fulminant pneumococcal native aortic valve endocarditis and perforation in a young male patient with chronic alcoholism and splenectomy who exhibited poor compliance to pneumococcal prophylaxis.© 2019 Royal College of Physicians.
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