• John McAuley, Richard van Gröningen, and Christopher Green.
• Department of Neurostimulation, Royal London Hospital, Whitechapel, London, UK. Queen Mary University of London, London, UK.
• Neuromodulation. 2013 Nov 1;16(6):530-6; discussion 536.

Objective€‚ Spinal cord stimulation (SCS) by high-frequency electrical pulses has been used since the early 1970s for relief of chronic intractable pain following limb amputation. The long-€term effectiveness of SCS for amputation-€related pain with ongoing after-care is reviewed by assessment of all such cases managed over 20 years in the Neurostimulator Clinic at the Royal London Hospital.Materials And Methods€‚ Twelve amputation-€related pain patients had quadripolar paddle electrodes (Resume; Medtronic Inc., Minneapolis, MN, USA) inserted epidurally by laminectomy over the thoracic or cervical dorsal spinal cord and connected to remotely controlled subcutaneously implanted stimulators (Itrel2, Itrel3, Synergy; Medtronic).Results€‚ Two of 12 patients had unsuccessful stimulation, one despite repeated electrode revisions. Two were subsequently lost to follow-€up, one had delayed spontaneous resolution of phantom limb pain, one had a technical fault, and one had gradually waning benefit over 19 years. In the remaining five patients having ongoing follow-up, self-€reported initial and final magnitudes of pain relief were unchanged, with a mean (SD) of 66% (18.2%). Benefits calculated from local and general visual analogue pain scores were similarly unchanged (initial local 48.8% [18.7%]; final local 50.0% [17.6%]; initial general 60.8% [10.9%]; final general 57.9% [12.3%]). Continued successful stimulation often required frequent changes of stimulating electrode contacts. Revision procedures for technical problems or pain at the battery site were universally successful.Conclusions€‚ Successful SCS in some patients with amputation-€related pain otherwise resistant to treatment indicates that the procedure merits continued use with further efforts to refine technique.© 2012 International Neuromodulation Society.

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