• Pablo Antonio Kuri-Morales, Guadalupe Díaz Del Castillo-Flores, Andrés Castañeda-Prado, and Salma Rosario Pacheco-Montes.
• Universidad Nacional Autónoma de México, Faculty of Medicine, Ciudad de México.
• Gac Med Mex. 2019 Jan 1; 155 (5): 423-429.

IntroductionInfluenza epidemics are of higher risk at the extremes of life and in people with comorbidities. Effective vaccination prevents the occurrence of serious cases and decreases mortality.ObjectiveTo describe deaths from influenza with a history of timely vaccination, from the 2010 to the 2018 season in Mexico.MethodCross-sectional, descriptive study where the Influenza Epidemiological Surveillance System database was used.ResultsFrom 2010 to 2018, 65 vaccinated individuals died from influenza, from which 55% of cases (n = 36) were due to type A (H1N1), 51% (n = 33) were females, median age was 57 years, 21 % (n = 14) did not meet the operational definition of influenza-like illness or severe acute respiratory infection, 83% (n = 54) had at least one comorbidity, with the most common being diabetes mellitus and hypertension (32% each); 55% (n = 36) of deaths received antiviral treatment and only 8% (n = 5) had no comorbidities and received treatment with oseltamivir.ConclusionsDeaths from influenza with timely vaccination represent a very low percentage of the totality. Vaccination against influenza has been a specific prevention strategy that decreases disease burden.Copyright: © 2019 Permanyer.

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