• Gac Med Mex · Jan 2020

    Neurological repercussions of changes in cerebral blood flow in neonates undergoing cardiovascular surgery.

    • Laura Carina Feria-Kaiser, Mario Enrique Rendón-Macías, Manuel Martínez-Meraz, María Del Rocío Méndez-Méndez, and Héctor Jaime González-Cabello.
    • Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Pediatric Hospital. Mexico City, Mexico.
    • Gac Med Mex. 2020 Jan 1; 156 (2): 109-116.

    IntroductionSurgery for congenital heart disease can generate cerebral perfusion-associated alterations with neurological repercussions.ObjectiveTo analyze the relationship of peri-surgical cerebrovascular resistance index (RI) with mediate neurological functions after congenital heart disease surgery.MethodProspective cohort study of 34 neonates in whom basilar artery RI, serum oxygen, carbon dioxide and lactate levels were determined before and after palliative or corrective procedures. We related pre-surgical RI with post-surgical ability to initiate the enteral route or to restore unassisted spontaneous breathing.ResultsThree groups were formed: 79 neonates with high RI (> 0.73), 73 with normal RI (0.63 to 0.73) and eight with low RI (< 0.63). In the former group, high RI persisted in the postoperative period, with persistent hyperlactatemia and hypoxia; in 86 %, the enteral route could not be initiated, and neither could assisted ventilation be withdrawn. In the second group, RI remained within normal values. In the third group, although RI, serum lactate and arterial oxygen pressure tended to normalize, 71 % had severe neurological damage.ConclusionsRI changes were common, although neurological damage appears to occur more commonly when RI remains high, possibly associated with low cerebral blood flow.Copyright: © 2020 Permanyer.

      Pubmed     Free full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…