• Hippokratia · Jan 2019

    Case Reports

    Efficacy and safety of Glecaprevir/Pibrentasvir in the treatment of mixed cryo-globulinemia due to chronic hepatitis C cirrhosis in a patient with chronic kidney disease.

    • N Papadopoulos, S Flouda, E Sveroni, M C Tatarida Palla, and V German.
    • 1 Department of Internal Medicine, 417 Army Share Fund Hospital of Athens, Greece.
    • Hippokratia. 2019 Jan 1; 23 (1): 30-32.

    BackgroundCurrently, direct-acting antivirals (DAAs) are the first-line treatment for patients with chronic hepatitis C (CHC) and mixed cryoglobulinemia syndrome (MCS). However, the prognosis is variable as the achievement of sustained virological response (SVR) is not always associated with clinical remission of MCS.Case ReportWe describe a case of CHC-MCS treated with the new DAA combination Glecaprevir/Pibrentasvir (GLE/PIB). The reported patient achieved SVR accompanying by complete clinical remission of MCS.ConclusionPatients with CHC-MCS vasculitis would benefit from antiviral treatment with GLE/PIB. HIPPOKRATIA 2019, 23(1): 30-32.Copyright 2019, Hippokratio General Hospital of Thessaloniki.

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