• J Postgrad Med · Jan 2019

    Case Reports

    Emphysematous osteomyelitis caused by Salmonella typhi in beta thalassemia major.

    • P N Doctor, M Verma, A Varaiya, and R H Merchant.
    • Department of Paediatrics, Nanavati Super Speciality Hospital, Vile Parle West, Mumbai, Maharashtra, India.
    • J Postgrad Med. 2019 Jan 1; 65 (1): 41-43.

    AbstractThere have been various cases of salmonella osteomyelitis reported in sickle cell anemia. We present a case of emphysematous osteomyelitis caused by Salmonella typhi in a 29-year-old beta thalassemia major patient. Diagnosis of emphysematous osteomyelitis was confirmed by computed tomography and magnetic resonance imaging, and culture of pus drained during surgical debridement confirmed the causative microorganism, Salmonella typhi. Antimicrobials were given according to microbiological sensitivity for a period of 8 weeks. Our patient also received hyperbaric oxygen therapy. At the end of therapy, he was afebrile and laboratory parameters normalized with a residual joint deformity which developed within 3 months.

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