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Observational Study
Alterations of carbohydrate metabolism during pregnancy. Effects on the mother and new born infant.
- Borja Guerrero Cervera, María Morales-Suarez-Varela, Alfredo Perales Marin, Isabel Peraita-Costa, Beatriz Marcos Puig, Agustin Llopis-Morales, and Agustin Llopis-Gonzalez.
- Área de Medicina Preventiva y Salud Pública, Departamento de Medicina Preventiva y Salud Pública, Ciencias de la Alimentación, Toxicología y Medicina Legal, Universidad de Valencia, Burjassot, Valencia, España.
- Med Clin (Barc). 2020 Feb 28; 154 (4): 119-124.
IntroductionGestational diabetes is the pathology that most frequently causes medical alterations in pregnancy. The objective of this study was to assess the relationship between the presence of alterations in the metabolism of carbohydrates during pregnancy and the risk of adverse obstetric outcomes in mother and foetus.Patients And MethodAn observational study was conducted on 799 women who had just given birth. The clinical and obstetric characteristics of the patients, as well as the data related to pregnancy and delivery, including the state of the new born infant were analysed. The information was evaluated in relation to the alterations in carbohydrate metabolism.Results And DiscussionFor women with gestational diabetes a 2.64 times greater risk of loss of foetal well-being and 3.14 times greater risk of requiring hospitalization during pregnancy were found. For pregnant women with carbohydrate intolerance, a 2.61 times higher risk of requiring episiotomy in vaginal delivery, a 7.54 times greater risk of finding loss of foetal well-being, and a 2.06 times greater risk of requiring hospitalization were found. The group with carbohydrate intolerance behaved similarly to that with diabetes.ConclusionsThe group with intolerance to carbohydrates is a little studied group and significant obstetric alterations were found compared to the control group and similar to those of the gestational diabetes group.Copyright © 2019 Elsevier España, S.L.U. All rights reserved.
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