• Tabinda Nawaz Khan, Farhan Raza Khan, and Syed Yawar Ali Abidi.
• Dr. Tabinda Nawaz Khan, BDS, MDS. Assistant Professor, Department of Science of Dental Materials, Dow Dental College, Dow University of Health Sciences, Karachi, Pakistan.
• Pak J Med Sci. 2020 Mar 1; 36 (3): 544-549.

ObjectiveTo compare the microleakage around resin modified glass ionomer cement (RMGIC) based sealants and flowable resin based sealants placed with or without ameloplasty in extracted human teeth.MethodsThis in-vitro experimental study was conducted at the Operative Dentistry Department, Dow University of Health Sciences, Karachi, Pakistan from June 2017 to December 2018. Sixty extracted human molars and premolars were assigned to four groups (n=15) each, according to the type of fissure sealant (flowable resin based sealant or resin modified glass ionomer based sealant) used and either placed with or without ameloplasty. Specimens were thermocycled and then immersed in 1% methylene blue for 24 hours. Specimens were then sectioned and examined using stereo-microscope (50X) for microleakage that was scored on an ordinal scale. Mann-Whitney U test and Ordinal regression were applied. Level of significance kept at 0.05.ResultsThere was a statistically significant difference (p-value <0.001) between the two sealant types for the microleakage scores. Sealants placed with ameloplasty demonstrated significantly higher microleakage values (p-value <0.001).ConclusionMicroleakage was found to be more pronounced in RMGIC based sealants compared to the resin based sealants. Ameloplasty resulted in higher leakage around the sealants irrespective of the chemistry of material.Copyright: © Pakistan Journal of Medical Sciences.

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