• Rev Assoc Med Bras (1992) · Jan 2020

    Review

    HIV-related nephropathy: new aspects of an old paradigm.

    • Érica Lofrano Reghine, Renato Demarchi Foresto, and Gianna Mastroianni Kirsztajn.
    • Departamento de Medicina (Nefrologia) da Universidade Federal de São Paulo, São Paulo, SP, Brasil.
    • Rev Assoc Med Bras (1992). 2020 Jan 13; 66Suppl 1 (Suppl 1): s75-s81.

    AbstractThe scenario of infection by the human immunodeficiency virus (HIV) has been undergoing changes in recent years, both in relation to the understanding of HIV infection and regarding the treatments available. As a result, the disease, which before was associated with high morbidity and mortality, is now seen as a chronic disease that can be controlled, regarding both transmission and symptoms. However, even when the virus replication is well controlled, the infected patient remains at high risk of developing renal involvement, either by acute kidney injury not associated with HIV, nephrotoxicity due to antiretroviral drugs, chronic diseases associated with increased survival, or glomerular disease associated to HIV. This review will cover the main aspects of kidney failure associated with HIV.

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