• Demet Yavuz, Mehmet Derya Demirağ, Rahman Yavuz, Düriye Sila Karagöz Özen, and Zeynep Banu Ramazanoğlu.
• Clinic of Internal Medicine, Samsun Education and Training Center, University of Health Sciences, Samsun, Turkey
• Turk J Med Sci. 2020 Apr 9; 50 (2): 298-303.

Background/AimDeficient levels of vitamin D are an important factor in the pathogenesis of some neurodegenerative diseases. The aim of this study is to determine the relationship between vitamin D deficiency and depression status and sleep disorders of patients on dialysis.Materials And MethodsIn this cross-sectional study, 121 hemodialysis patients were enrolled. All patients had been on hemodialysis for at least six months at the time of the study. Sleep quality and depression status were measured by using specific inventories. All the patients filled out Pittsburg Sleep Quality Index (PSQI) and Beck Depression Inventory (BDI), and gave blood samples. Vitamin D levels were measured for 121 patients, and statistical analysis was done by using SPSS.ResultsRegression analyses demonstrated that low levels of 25(OH)D and high BDI score were independent risk factors for poor sleep quality [ORs were 0.668 (0.566–0.789), 1.080 (1.001–1.164), and 1.080 (1.001–1.164), respectively].ConclusionOur results suggest that deficiency of 25(OH)D is an important independent risk factor for poor sleep quality in hemodialysis patients.Our results suggest that deficiency of 25(OH)D is an important independent risk factor for poor sleep quality in hemodialysis patients.

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