• Turk J Med Sci · Apr 2020

    Prognostic role of homeostasis model assessment and oral glucose tolerance test in nondiabetic patients with Bell’s palsy

    • Tuğba Karagöz, Ömer Bayir, Emel Çadalli Tatar, Erman Çakal, Ali Özdek, Kemal Keseroğlu, Mustafa Şahin, and Mehmet Hakan Korkmaz.
    • Otorhinolaryngology and Head and Neck Surgery Clinic, Kaman State Hospital, Kırşehir, Turkey
    • Turk J Med Sci. 2020 Apr 9; 50 (2): 405-410.

    Background/AimWe aimed to revealthe incidence and predictive role of insulin resistance and distorted oral glucose tolerance test in nondiabetic patients withBell’s Palsy (BP).Materials And MethodsEighty-sixpatients with BP and 28 control subjects; all with normal blood glucose levels and no history of diabetes, were enrolled in the study. We investigated insulin resistance (IR) in all subjects, in terms of HOMA-IR greater than 2.7. Sixty-two of the patients also underwent an oral glucose tolerance test (OGTT).ResultsThe mean HOMA-IR value was significantly increased in patients, compared to the control group (3.2 vs 1.6; P < 0.01). IR was detected more in BP patients than in controls (P < 0.05). The patients with higher HOMA-IR values had more severe facial dysfunction at the initial presentation and complete recovery time took longer than the patients with normal HOMA-IR value (75 days vs 42 days; P < 0.05). Following a 2h-OGTT, impaired glucose tolerance and newly diagnosed DM were found in 60% of the patients. Recovery time was significantly longer in prediabetics and newly diagnosed diabetic patients than in patients with normal glycemia (68 days, 52 days, and 32 days, respectively; P < 0.01).ConclusionThere is a strong linkage between HOMA-IR value and BP prognosis so HOMA-IR value may have a significant role of predicting BP prognosis at presentation.This work is licensed under a Creative Commons Attribution 4.0 International License.

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